This week, Dom is joined by Maz Jobrani, writer and star of the new movie, Jimmy Vestvood: Amerikan Hero!

This week, Dom is joined by guest Amir K!

This week, Dom is joined by returning guest Kirk Fox!

This week, Dom is joined by guest Harland Williams!

This week, Dom is joined by guest Fahim Anwar!

This week, Dom is joined by guest Jordan Rock!

This week, Dom is joined by guest Theo Von!

This week, Dom is joined by guest Ahmed Ahmed!

This week, Dom is joined by guest Felipe Esparza. 

This week, Dom is joined by guest Todd Shapiro of the Sirius XM Radio program The Todd Shapiro Show! Check out Todd Shapiro weekdays from 4-6p on Sirius CH 168. 

This week, Dom is joined by guest Ari Shaffir.

This week, Dom is joined by comedian Adam Ray. 

This week, Dom is joined by guest Chris Redd. 

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Owen Benjamin!

This week on Dom Irrera Live from The Laugh Factory, Dom is joined by guest Chaunté Wayans.

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by comedian Bill Dawes. 

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Brody Stevens. 

Fresh off of the release of his new animated comedy, F is for Family, comedian Bill Burr joins Dom on this week's episode of Dom Irrera Live from the Laugh Factory.

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Jenny Johnson.

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Matt Rife!

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by comedian Eleanor Kerrigan!

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by comedian Kelsey Cook.

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Tom Dreesen. 

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by guest Tiffany Haddish. 

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by comedian Esther "Little Esther" Povitsky.

This week on Dom Irrera Live from The Laugh Factory, Dom is joined by comedian Rick Glassman. 

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by guest Eddie Ifft. 

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by comedian/star of Undateable, Chris D'Elia. 

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by comedian Alonzo Bodden. 

This week, comedian Maronzio Vance talks with Dom about Twitter, worst gigs, Scientology, and Hollywood Shuffle.

This week on Dom Irrera Live from the Laugh Factory, Dom is joined by comedian Steve Hofstetter.

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by special guest Craig Robinson. 

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by special guest Kate Quigley. 

This week on Dom Irrera Live From the Laugh Factory, guest Pauly Shore discusses growing up in a comedic enviroment, and how it has shaped his career. 

This week on Dom Irrera Live From the Laugh Factory, Dom is joined by comedian Beth Stelling. 

Dom Irrera is joined by Steve Simeone on this week's release of Dom Irrera Live From the Laugh Factory. 

Comedian, writer, and actor Nick DiPaolo talks with Dom about their past, The Sopranos, and Nick's favorite gigs & clubs. Subscribe on iTunes and Sticher! 

Comedian Tony Hinchcliffe returns to the show to discuss Joe Rogan, podcasts, his family, and more.  Subscribe on iTunes Here! or at Sticher Here!

Comedian Jessimae Peluso talks to Dom about accents, bowel movements, growing up, fetishes, relationships, and celebrities including Daniel Tosh and Bruce Willis.

Actor, writer and comedian Johnny Sanchez returns to the show to talk to Dom about breakdancing, the confederate flag controversy, and Bob Saget on Full House Vs. Bob Saget in real life.

Actor and comedian Lowell Sanders stops by the show to talk to Dom about rookie strip club mistakes, losing Star Search to a puppet, and their best drug stories.

Writer, actor and comedian Steve Byrne stops by the show to talk to Dom about why stand up comedy is better now than ever, their favorite stand up clubs, and picking up chicks at the Grove after they get out of a taping of The Price Is Right.

Comedian, actor, and writer Jeremy Hotz returns to the show to talk to Dom about the difference between movie fighting and real fighting, their best Siri stories, and how comedy movies don't get any respect.

Actor, writer, and comedian Adam Ray returns to the show to talk to Dom about his podcast "About Last Night" with Brad Williams, doing voice-overs for Bruce Willis, and meeting Paul McCartney at the Improv.

Actor, host and comedian Billy Gardell drops by the show to talk to Dom about Mike and Molly, getting kicked off a boat for being drunk and yelling at the captain, and having dinner with Bruce Springsteen.

Writer, Director and Producer, Michael Patrick King drops by the show to talk to Dom about Murphy Brown, improv Vs stand-up, and being bad Catholics.

Comedian, writer, and actor Rick Glassman returns to the show to talk to Dom about NBC's Undateable, who would win in a fight, and dunking to the point of arthritis.

Comedian, Director and Producer Brian Redban returns to the show to talk to Dom about Hookers, Comedy Drama, and stealing other comedians' essence.

Comedian, actor, and director Ahmed Ahmed returns to the show to talk to Dom about Bill Cosby, being on TMZ, and having the same name as a most wanted terrorist.

Comedian, actor, and writer Dov Davidoff returns to the show to talk to Dom about taking pills and passing out on stage, New York City Vs. Los Angeles, and crazy-ex girl friend stories.

Comedian, actor, and philanthropist Tom Dreesen returns to the show to talk to Dom about touring with Frank Sinatra, the problems with AA, and dealing with those guys back home who never left the neighborhood.

Comedian, actor, and writer Kirk Fox stops by the show to talk to Dom about getting Tinnitus from his show "The Test," playing Tennis with Dr. Phil, and being with a girl that's too hot to bring around.

Comedian, actor and writer Andrew Santino returns to the show to talk to Dom about their alcoholism, YouTube haters, and shooting hoops with George Clooney.

Comedian, writer, and pro-athlete Michael Kosta stops by the show to talk to Dom about tennis, bad birthdays, and how a diminishing libido can greatly increase your productivity.

Comedian, actor, and party-starter Darren Carter stops by the show to talk to Dom about rap lyrics, blue-collar vs. redneck, and hanging out with the New Kids on the Block.

Comedian, actor and writer Al Madrigal stops by the show to talk to Dom about getting on The Daily Show, setting a good example for kids, and how to fire people.

Comedian, writer and actor Dave Attell stops by the show to talk to Dom about Catholic guilt, the difficulties of working clean, and why hotel porn doesn't do the job.

Comedian, actor and voice artist Andy Kindler stops by the show to talk to Dom about about Woody Allen movies, Jay Leno's closet full of Doritos, and when "jew" was a punchline.

Comedian, actor and writer Dan Ahdoot stops by the show to talk to Dom about about ISIS, Falafel Phil, and the dangers of dating comedians.

Comedian, actor and artist Tom Wilson stops by the show to talk to Dom about bullies, Back to the Future, and how dangerous the Comedy Store was in the 80's.

Comedian, actor, and writer Flip Schultz drops by the show to chat with Dom about bombing, clowns, and "borrowing" jokes from Sam Kinison.

Comedian, writer, and prankster Grant Cotter drops by the show to chat with Dom about cocky comedians, skanky strippers, and making girls cry.

Comedian, actor, and writer Jake Johannsen drops by the show to chat with Dom about Robin Williams, the NSA, and offending hookers with golf-claps.

Comedian, actor, and writer Tom Papa makes a return visit to chat with Dom about drinking and drugging, not apologizing for your comedy, and his fall-back plans for when he crashes and burns. 

Comedian and actor Bill Dawes returns to the show to tell Dom about getting in fights, being on Broadway, and getting married to please your mother.

Comedian, actor and writer Kira Soltanovich makes a return visit to chat with Dom about not knowing how to be Jewish, her top 3 favorite comedians, and mentally quitting comedy a couple times a week.

Comedian, TV host, and actor John Henson makes a return visit to chat with Dom about Wipeout, giving people the "full court press", and the horrors of discovering the porn you're watching was filmed in your house!

Comedian and DeathSquad podcaster Justin Martindale drops by the show to chat with Dom about the Sunset Strip in the 80s, how easy it is to get drunk when you're constantly offered free drinks, and their favorite curse words.

Comedian and podcaster Todd Glass makes a return visit to chat with Dom about coming up in Philly together, the joy of busting balls, and the low-stakes curse of wishing fatigue upon someone.

Actress, comedian, and writer Erin Foley drops by the show to talk with Dom about messed up intros, coming out of the closet, and Derek Jeter's retirement. 

Comedian and actor Bill Burr makes his hat trick appearance! He and Dom survey The Beatles' greatest hits, talk sports up and down, and get into their favorite hacky jokes.  

Comedian, actor, and writer Elon Gold drops by the show to pay tribute to Joan Rivers, show off some impressions, and explore a recent unfortunate hate incident.

Comedian John Heffron drops by the show to chat with Dom about their favorite dirty word, social media, and life on the road.

Comedian, writer, and actor Rick Overton makes a return visit to pay tribute with Dom to the legendary Robin Williams. 

Actor and comedian Gerry Bednob drops by the show to chat with Dom about their roots, why it's dumb to say you're "crushing it", and Robin Williams.  

Dom welcomes comedian, writer, and podcast host Greg Fitzsimmons back to the show to talk about being called a legend, passive-aggressive hosts, and Greg's new special, Life On Stage.

Actor, writer, and comedian Rick Glassman drops by the show to talk with Dom about Undateable the TV show, being undateable in real life, and basketball.

Comedian and actor Mike Ivy drops by the show to talk with Dom about prejudices, gambling on the job, and the ideal woman.

On an emotional episode, comedian, writer, and actor Cathy Ladman opens up to Dom about her struggles with anorexia, standup war stories, and Judaism.

Actor, impressionist, and comedian Jonathan Kite drops by to chat with Dom about 2 Broke Girls, disappointing idols, and cartoon voices.  

Comedian Bob Zany drops by the show to chat with Dom about puppet acts, the Comedy Awards, and what it means to be risky in show business.

Comedian and podcast host Brad Williams drops by the show to chat with Dom about Canadian hecklers, judging athletes, and being a dwarf comic. 

Legendary actor/comedian Allan Havey drops by the show to talk with Dom about great TV, miming skills, and name-dropping.

The bubbly and charming Arden Myrin drops by the show to chat with Dom about MadTV, seeing comedians naked, and setting off airport metal detectors with your crotch. 

Richard Lewis drops by the show to chat with Dom about old references, life on the road, and their post-mortem marquees.

Taylor Williamson visits Dom to talk America's Got Talent, the road to being a comic, and some interesting words to look up.  

Sarah Tiana swings by the show to talk with Dom about the art of the roast, celebrities' odd relationships with servers, and most importantly, football. 

Famed radio DJ and comic Frazer Smith makes his hat trick appearance on the show, talking with Dom about Vegas, stand-up etiquette, and how to behave around celebrities.

The smoothest comic in the biz makes a return visit to Dom Irrera to talk growing up in Chicago, the comedy strike, and Sinatra. 

The Impractical Jokers swing by the show to talk with Dom about the art of the prank, throwing chicken in people's faces, and why it's important to make fun of your friends. 

This week comedian Josh Wolf drops by the show to chat with Dom about parenting, early encounters with Joey Diaz, and the art of hosting a naked survival show. 

This week comedian Duncan Trussell drops by the show to talk with Dom about enlightenment, social conspiracies, and the pursuit of Bigfoot. 

Angelo Cataldi, one of Philadelphia's top sports radio personalities, drops by to talk with Dom about...well...sports and radio. 

Ari Shaffir returns to the podcast this week to talk with Dom about comedian feuds and rising in the stand-up world. 

This week, Dom Irrera talks to comedian Jessimae Peluso (Girl Code) about alcohol preferences and chicken broth. 

This week, comedian Mark Schiff drops by to talk with Dom about pranks on the road, and a near-death flight experience with Jerry Seinfeld. 

This week, comedian Brian Redban drops by to talk with Dom a little about relationships, and a lot about porn. 

This week, comedian Tony Hinchcliffe and Dom Irrera chat about writing roast jokes, the concept of scissoring, and debate a sexuality change to boost their careers. 

This week, comedian Jim Florentine drops by to talk with Dom Irrera about strip clubs, talk show politics, and prank phone calls. 

On this week's episode, Joe Rogan returns to chat with Dom about UFC, his writing process, and quantum physics.